The two most critical components of Fire Prevention and Protection Science are Fire Detection and Suppression Systems, as protecting human life is the top priority. Among the urgent priorities, relevant regulations should be reviewed immediately, and comprehensive Fire Risk Analyses should be conducted without delay. British Standards (such as BS 9999) and NFPA regulations serve as excellent examples for us in this regard. These Fire Risk Analyses should be carried out, documented, and monitored by fire experts, particularly for public and government buildings. Additionally, it is essential to clearly define the authorities responsible for issuing Fire Permits. We extend our condolences to all of Türkiye and everyone affected by the fire.